SINGLE-CELL TECHNOLOGIES FOR THE STUDY OF ANTIBODY-SECRETING CELLS

Antibody-secreting cells (ASC), plasmablasts and plasma cells, are terminally differentiated B cells responsible for large-scale production and secretion of antibodies.ASC are derived from activated B cells, which may differentiate extrafollicularly or form germinal center (GC) reactions within secondary lymphoid organs.ASC therefore consist of sho

Abstract Background The specific genetic regulation of neural primordial cell determination is of great interest in stem cell biology.The Musashi1 (Msi1) protein, which belongs to an evolutionarily conserved family of RNA-binding proteins, is a marker for neural stem/progenitor cells (NS/PCs) in the embryonic and post-natal central nervous system (